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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
YWHAQ
All Species:
49.09
Human Site:
Y179
Identified Species:
90
UniProt:
P27348
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P27348
NP_006817.1
245
27764
Y179
L
N
F
S
V
F
Y
Y
E
I
L
N
N
P
E
Chimpanzee
Pan troglodytes
XP_525684
416
45456
Y350
L
N
F
S
V
F
Y
Y
E
I
L
N
N
P
E
Rhesus Macaque
Macaca mulatta
XP_001097635
245
27803
Y179
L
N
F
S
V
F
Y
Y
E
I
L
N
N
P
E
Dog
Lupus familis
XP_856222
224
25254
P164
Y
Y
E
I
L
N
N
P
E
L
A
C
T
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQV8
246
28068
Y181
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
E
Rat
Rattus norvegicus
P63102
245
27753
Y179
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518806
277
31320
Y212
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
E
Chicken
Gallus gallus
Q5ZMD1
245
27764
Y179
L
N
F
S
V
F
Y
Y
E
I
L
N
N
P
E
Frog
Xenopus laevis
Q8AVQ3
244
27740
Y179
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
D
Zebra Danio
Brachydanio rerio
Q5PRD0
244
27628
Y179
L
N
F
S
V
F
Y
Y
E
I
L
N
T
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29310
248
28209
Y182
L
N
F
S
V
F
Y
Y
E
I
L
N
S
P
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q20655
248
28049
Y181
L
N
F
S
V
F
F
Y
E
I
L
N
A
P
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34730
273
31043
Y184
L
N
F
S
V
F
Y
Y
E
I
Q
N
S
P
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.8
99.1
91.4
N.A.
80.4
80
N.A.
72.9
98.7
77.5
78.3
N.A.
76.6
N.A.
75.4
N.A.
Protein Similarity:
100
58.8
99.1
91.4
N.A.
90.6
91
N.A.
80.5
100
90.6
89.8
N.A.
85.8
N.A.
83.8
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
93.3
93.3
N.A.
93.3
100
86.6
93.3
N.A.
86.6
N.A.
80
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
100
N.A.
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
56.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
71.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
93.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% D
% Glu:
0
0
8
0
0
0
0
0
100
0
0
0
0
0
62
% E
% Phe:
0
0
93
0
0
93
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
93
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
93
0
0
0
8
0
0
0
0
8
85
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
93
0
0
0
8
8
0
0
0
0
93
31
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
93
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
93
0
0
0
0
0
0
0
0
47
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% T
% Val:
0
0
0
0
93
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
0
0
85
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _